Ab-DeliverIN™ is the first dedicated intracellular antibody delivery reagent. This lipid-based formulation is the first serum compatible reagent allowing the delivery of functional antibodies into living cells. Due to its unique properties, Ab-DeliverIN™ forms non-covalent complexes with antibodies through electrostatic and hydrophobic interactions. Consequently, chemical or genetic couplings are not necessary. In addition, delivered antibodies retain their structure and function. This feature makes Ab-DeliverIN™ an exclusive reagent allowing the antibody to reach its intracellular target. Ab-DeliverIN™ opens new fields of investigation in proteomics to elucidate complex molecular mechanisms or to design new potential therapies. For example, the intracellular delivery of blocking antibodies could inhibit and/or neutralize protein function.
- Functionally active antibodies delivery
- Highly efficient in many primary cells and cell lines
- Serum compatible
- Biodegradable and no cytotoxicity
- Easy: straightforward protocol and ready-to-use
This product has met the following criteria: