Ser-Leu-Ile-Gly-Lys-Val-amide, >=95% (HPLC), solid

Code: S9192-1MG D2-231

Amino Acid Sequence

Ser-Leu-Ile-Gly-Lys-Val-NH2

Biochem/physiol Actions

Proteinase-activated receptor-2 (PAR2)-activating peptide.

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Amino Acid Sequence

Ser-Leu-Ile-Gly-Lys-Val-NH2

Biochem/physiol Actions

Proteinase-activated receptor-2 (PAR2)-activating peptide.

Proteinase-activated receptor (PAR-2) is a member of proteolytically cleaved receptors. It is activated by a synthetic peptide (SLIGKV), that is exposed after trypsin cleavage of the amino terminus. PAR-2 stimulates an increase in cytosolic Ca2+ ion concentration.

Other Notes

Lyophilized from 0.1% TFA in H2O

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

assay≥95% (HPLC)
formsolid
Gene Informationmouse ... Insrr(23920)
InChI keyHOWDUIVVWDUEED-WAUHAFJUSA-N
InChI1S/C28H54N8O7/c1-7-17(6)23(36-27(42)20(12-15(2)3)34-25(40)18(30)14-37)28(43)32-13-21(38)33-19(10-8-9-11-29)26(41)35-22(16(4)5)24(31)39/h15-20,22-23,37H,7-14,29-30H2,1-6H3,(H2,31,39)(H,32,43)(H,33,38)(H,34,40)(H,35,41)(H,36,42)/t17-,18-,19-,20-,22-,23-/m0/s1
Quality Level200
SMILES stringCC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O
storage temp.−20°C
UniProt accession no.Q9WTL4
Cas Number190383-13-2
This product has met the following criteria: