SGK1 (delta1-60, S422D), active human, recombinant, expressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged), buffered aqueous soluti

Code: S8939-2UG D2-231

Biochem/physiol Actions

Kinase assays.

The serum- and glucocorticoid-regulated kinase (SGK1) has a role in the hormonal regulation of ion channels and pumps. It has bee...


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Biochem/physiol Actions

Kinase assays.

The serum- and glucocorticoid-regulated kinase (SGK1) has a role in the hormonal regulation of ion channels and pumps. It has been associated with cancers. The protein modulates nitric oxide production by activating NO synthase. SGK1 protects cells from apoptosis and oxidative stress.

General description

The serum- and glucocorticoid-regulated kinase (SGK1) is a member of the AGC kinase family and the gene encoding it is localized on human chromosome 6q23.

Legal Information

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Physical form

Solution in 50 mM Tris-HCl, pH 7.5, 0.1 mM EGTA, 0.1% β-mercaptoethanol, 0.15 M NaCl, 0.03% Brij® L23, 1 mM benzamidine, 0.2 mM PMSF. and 270 mM sucrose.

Unit Definition

One unit of SGK1 = 1 nmol phosphate incorporated into crosstide substrate peptide in one minute.

formbuffered aqueous solution
Gene Informationhuman ... SGK1(6446)
mol wt~48 kDa by SDS-PAGE
Quality Level200
recombinantexpressed in baculovirus infected Sf9 cells (truncated human sequence (a.a. 1-60 deleted, S422D mutation)-histidine-tagged)
shipped indry ice
storage temp.−70°C
UniProt accession no.O00141
This product has met the following criteria: