Biochem/physiol Actions

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. Known to be a rich source of drug metabolizing enzymes including P-450, these pools are useful in the study of xenobiotic metabolism and drug interactions.

The hepatic S9 pools from a variety of biological sources represent the post-mitochondrial supernatant fraction from homogenized liver. They are known to be a rich source of drug metabolizing enzymes including P-450. S9 pools are useful in the study of xenobiotic metabolism and drug interactions. They are used in the Ames test, which is a method that uses bacteria to test if a given chemical causes mutations in the genetic material of a given test organism.

Physical form

Supplied as a solution in 150 mM KCl, 50 mM Tris buffer, pH 7.2 and 2 mM EDTA.