beta-Defensin 1 human, >=98% (HPLC and SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder (from 10 mM acetic acid)

Code: D9565-5UG D2-231

Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide...


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Amino Acid Sequence

Asp-His-Tyr-Asn-Cys-Val-Ser-Ser-Gly-Gly-Gln-Cys-Leu-Tyr-Ser-Ala-Cys-Pro-Ile-Phe-Thr-Lys-Ile-Gln-Gly-Thr-Cys-Tyr-Arg-Gly-Lys-Ala-Lys-Cys-Cys-Lys [Disulfide bridges 5-34, 12-27, and 17-35]

Biochem/physiol Actions

A small cationic peptide which demonstrates anti-microbial activity. Originally isolated from human plasma, this substance is constitutively expressed in mucosal membrane epithelium.

General description

Chemical structure: peptide

antibiotic activity spectrumfungi, viruses, Gram-positive bacteria, Gram-negative bacteria
assay≥98% (HPLC and SDS-PAGE)
formlyophilized powder (from 10 mM acetic acid)
Gene Informationhuman ... DEFB1(1672)
mode of actioncell wall synthesis | interferes
mol wtestimated mol wt 3.9 kDa
Quality Level200
recombinantexpressed in E. coli
storage temp.−20°C
UniProt accession no.P60022
This product has met the following criteria: