Dexamethasone, meets USP testing specifications

Code: D9184-5G D2-231

Application

Dexamethasone was used as medium supplement in the following studies:To investigate the osteogenic differentiation and chondrogenic differentiation of bone marrow...


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Your Price
£2,310.00 5G
£2,772.00 inc. VAT

Application

Dexamethasone was used as medium supplement in the following studies:To investigate the osteogenic differentiation and chondrogenic differentiation of bone marrow mesenchymal stem cells (MSCs).In α-MEM (minimum essential medium) for inducing the osteogenic and adipogenic differentiation in mesenchymal stem cells from human bone marrow and umbilical cord blood.For the isolation and characterization of mesenchymal stem cells isolated from 6- to 8-week-old C57BL/6J mice.

Biochem/physiol Actions

Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.

General description

Dexamethasone is an anti-inflammatory glucocorticoid with a range of effects on cell survival, cell signaling and gene expression. It is useful for study of apoptosis, cell signaling pathways and gene expression.

Packaging

1, 5 g in glass bottle

100 mg in glass bottle

agencymeets USP testing specifications, USP/NF
assay97.0-102.0%
biological sourcesynthetic (organic)
formsolid
Gene Informationhuman ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)rat ... Ar(24208), Nr3c1(24413), Tnf(24835)
InChI keyUREBDLICKHMUKA-CXSFZGCWSA-N
InChI1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
mp262-264 °C (lit.)
Quality Level200
shipped inambient
SMILES stringC[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
storage temp.2-8°C
Code
Description
Unit Size
List Price
Qty
D9184-100MG
Unit:100MG
List Price: £145.00
Source:List Price
ADD
D9184-1G
Unit:1G
List Price: £765.00
Source:List Price
ADD
Cas Number50-02-2
This product has met the following criteria: