Application
Facade®-EPC has been used to produce bicelles for nuclear magnetic resonance (NMR) experiments. It may be used in crystallization of cytochrome P450 2B subfamily proteins, CYP2B35 and CYP2B37.
Biochem/physiol Actions
Facade® is a mild rim forming surfactants, used in the synthesis of isotropic bicelles which prevents unfolding of soluble globular domains of large membrane proteins.
Facade® EPC/FA-7 (3α-hydroxy-7α,12α-di-(((2-(trimethylamino)ethyl)phosphoryl)ethyloxy)-cholane) having phosphocholine groups helps in preparing smaller micelles than the facial amphiphiles (FAs) with nonionic sugar groups.
Legal Information
Facade is a registered trademark of Avanti Polar Lipids, Inc.
Packaging
5 mL Amber Glass Screw Cap Vial (850539P-25mg)
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