Dextran sulfate sodium salt from Leuconostoc spp., Mr 5,000

Code: 31404-25G-F D2-231

Application

Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped ...


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Application

Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.

Biochem/physiol Actions

Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.

Preparation Note

prepared from dextran with Mr ~5000

Quality Level200
Quality Level200
mol wtMr 5,000
solubilityH2O: 0.1 g/mL, clear, colorless to slightly yellow
solubilityH2O: freely soluble 50 mg/mL, clear
compositionSulfur Content, 16.0-20.0%
loss≤10% loss on drying
loss≤0.2% loss on drying, 105 °C, 2 h
formpowder
gradeACS reagent, reag. Ph. Eur.
gradepuriss. p.a.
InChI1S/K.Mn.4O/q+1;;;;;-1
cation tracesFe: ≤20 mg/kg
cation tracesCu: ≤5 mg/kg
cation tracesPb: ≤20 mg/kg
InChI keyVZJVWSHVAAUDKD-UHFFFAOYSA-N
anion traceschloride, chlorate (as Cl-): ≤30 mg/kg
anion tracessulfate (SO42-): ≤100 mg/kg
impurities≤0.003% total nitrogen (N)
impurities≤0.2% in water insoluble matters
assay≥99%
SMILES string[K+].[O-][Mn](=O)(=O)=O
Code
Description
Unit Size
List Price
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31404-5G-F
Dextran sulfate sodium salt from Leuconostoc spp., Mr 5,000

Unit:5G
List Price: £87.70
Source:List Price
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Cas Number9011-18-1
This product has met the following criteria: