2-Naphthyl phosphate disodium salt, 97%

Code: N6005-1G-A D2-231

Application

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrat...


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Your Price
£55.75 1G
Discontinued
£66.90 inc. VAT

Application

As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

2-Naphthyl phosphate disodium salt has been used to study its binding characteristics onto alumina.

Biochem/physiol Actions

NADH is a coenzyme that functions as a regenerating electron donor in catabolic processes including glycolysis, ß-oxidation and the citric acid cycle (Krebs cycle, TCA cycle). It participates in cell signaling events as well, for example as a substrate for the poly (ADP-ribose) polymerases (PARPs) during the DNA damage response. The NAD+/NADH dependent sirtuins play key roles in stress responses during events involving energy metabolism, with implications in cancer biology, diabetes and neurodegenerative disease.As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Packaging

Packaged by solid weight.

1, 5, 25 g in poly bottle

1, 5 g in glass bottle

Quality Level200
Quality Level200
shipped inwet ice
SMILES stringO.[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]2O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n4cnc5c(N)ncnc45)[C@@H](O)[C@H]2O
SMILES stringO.[Na+].[Na+].[O-]P([O-])(=O)Oc1ccc2ccccc2c1
assay≥94% (spectrophotometric assay)
assay≥94% (HPLC)
assay97%
InChI1S/C21H29N7O14P2.2Na.H2O/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;;1H2/q;2*+1;/p-2/t10-,11-,13-,14-,15-,16-,20-,21-;;;/m1.../s1
InChI1S/C10H9O4P.2Na.H2O/c11-15(12,13)14-10-6-5-8-3-1-2-4-9(8)7-10;;;/h1-7H,(H2,11,12,13);;;1H2/q;2*+1;/p-2
InChI keyFWBNCIFELNNJCX-UHOVGGJYSA-L
InChI keyVZEQFWJGQGFKLL-UHFFFAOYSA-L
storage temp.−20°C
storage temp.−20°C
Code
Description
Unit Size
List Price
Qty
N6005-5G-A
Unit:5G
List Price: £218.72
Source:List Price
Discontinued
Cas Number31681-98-8
This product has met the following criteria: