Application

Acetic anhydride may be used as a reactant to synthesize:3-acetoxybenzoic acid by reacting with 3-hydroxybenzoic acid6-dimethylamino-2,3-naphthalenedicarboxylic anhydride, a precursor to prepare 6-dimethylaminonaphthalimide

Acetic anhydride was used in the following studies:Lipozyme TL IM (commercial immobilized lipase from Thermomyces lanuginosus) catalyzed acetylation of essential clove oil. As acetyl donor to investigate the lipase catalyzed acetylation of nanofibrillated cellulose (NFC).Synthesis of N-substituted pyrazolines.Acetylation of Barnyardgrass (Echinochloa crus-galli) starch.

General description

Acetic anhydride participates in the Friedel-Craft′s intramolecular cyclization reaction of cyclopropyl ketones to afford the tetralones. It has been reported to promote the Knoevenagel condensation of various aldehydes and activated methylene compounds.

Acetic anhydride is a carboxylic acid anhydride commonly used as an acetylating agent for amines and alcohols.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Packaging

1 L in glass bottle

100, 4×100, 500 mL in glass bottle