Application

Titanium-ate enolates prepared from ketones by Ti(OiPr)4 and LDA underwent efficient radical trifluoromethylation providing trifluoromethyl ketones in good yield. Used in directed ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.

General description

This material is in a solution of THF/Hexanes (ca. 1:7 ratio, respectively)

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Packaging

4×25, 100, 500 mL in Sure/Seal™

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.