Application

Lithium diisopropylamide solution (LDA) can be used:As an initiator in the anionic polymerization of D,L-lactide and methyl methacrylate.To facilitate ester enolization.To convert carboxylic acids to enediolate intermediates for preparing trifluoromethyl ketones.In ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.To catalyze ortholithiation and Fries rearrangement of aryl carbamates.As a promoter in the isomerization of allylic ethers to (Z)-propenyl ethers.

General description

Lithium diisopropylamide solution (LDA) is a sterically hindered non-nucleophilic strong base widely used in organic synthesis.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC

Packaging

The 25 mL Sure/Seal^™ bottle is recommended as a single-use bottle. Repeated punctures will likely result in decreased performance of product.

4×25, 100, 4×100, 800 mL in Sure/Seal™