Application

Sodium tert-butoxide may be used as a safe and effective alternative to sodium hydride for the coupling of hydroxyethyl adenine with diethyl p-toluenesulfonyloxymethanephosphonate to form 9-[2-(diethylphosphonomethoxy)ethyl]adenine (diethyl-PMEA), which is a key intermediate to prepare adefovir dipivoxil.It can also be used:To facilitate the coupling of aryl halides with benzene derivativesin the presence of 10-phenanthroline derivative.To activate first-row transition-metal pre-catalysts.As a base for the amination of aryl chlorides in the presence of a novel palladacyclic precatalyst.

Packaging

2.5 kg in poly bottle

5, 25, 100, 500 g in poly bottle

1.5 kg in glass bottle