Application
Lithium diisopropylamide can be used for the generation of carbanion or enolate anions from carbonyl group-containing compounds.It can also be used as a base in: The direct alkylation and acylation of ketones. The aldol condensation reaction. α-Selenation reaction. The synthesis of α, β- unsaturated carbonyl compounds from carbonyl compounds. The alkylation of acids, esters, amides, and nitriles. The initiation of anionic polymerization.
General description
Lithium diisopropylamide (LDA) is a hindered non-nucleophilic strong base that abstracts hydrogen from active carbon. It can be prepared from diisopropylamine and butyllithium in the presence of tetrahydrofuran.
Packaging
25, 100 g in glass bottle
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