Application

β-NADPH is suitable for use in:desaturation of fatty acidsan assay of desaturase activitythe histochemical detection of NADPH diaphorase activity in rat, rabbit and pheasant thoracic spinal cordthe measurement of glutathione in oligodendrocyte cultures

Biochem/physiol Actions

NADPH is an electron donor and a cofactor for many redox enzymes including nitric oxide synthetase.

β-NADPH is the reduced form of NADP⁺ generated by the pentose phosphate pathway. It serves as a carrier of reducing power and transfers H⁺ and 2 e^– to the oxidized precursors in the reduction reactions of biosynthesis. It is an essential coenzyme for the catalytic activity of enzymes such as glutathione reductase, diacetyl reductase, dihydrofolate reductase, glutamic dehydrogenase, p-hydroxybenzoate hydroxylase, NADPH-FMN oxidoreductase, nitrate reductase, and thioredoxin reductase. It is also a part of cytochrome P₄₅₀ electron transport systems.

Other Notes

Packaged based on solid weight.

Packaging

1, 5 g in poly bottle

25, 50, 100, 250, 500 mg in poly bottle

Preparation Note

Chemically reduced.