Inosine, >=99%

Code: I4125-25G D2-231

Application

Inosine has been used:as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.as a component in holidic (synthetic) medium and in ...


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Your Price
£108.00 25G
£129.60 inc. VAT

Application

Inosine has been used:as a medium supplement in nucleotide rescue experiments in pancreatic cancer cell lines.as a component in holidic (synthetic) medium and in larval two-choice preference assay.as a reference standard in mass spectroscopy.

Biochem/physiol Actions

Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.

General description

Inosine is a non-canonical nucleotide majorly present as monophosphate. It has ability to base pair with deoxythymidine, deoxyadenosine and deoxyguanosine. Incorporation of inosine in place of guanine modulates translational events. Inosine has antioxidant, anti-inflammatory and neuroprotective functionality. Inosine is prescribed as a therapeutic supplement for nerve injury, inflammation and oxidative stress. It modulates biological processes through adenosine receptors. Its enhances neurite outgrowth in depressive disorders via adenosine receptors. Inosine is also used for treating sepsis in infections.

Packaging

1, 5, 10, 25, 100 g in poly bottle

assay≥99% (HPLC)
InChI keyUGQMRVRMYYASKQ-KQYNXXCUSA-N
InChI1S/C10H12N4O5/c15-1-4-6(16)7(17)10(19-4)14-3-13-5-8(14)11-2-12-9(5)18/h2-4,6-7,10,15-17H,1H2,(H,11,12,18)/t4-,6-,7-,10-/m1/s1
mp222-226 °C (dec.) (lit.)
Quality Level200
SMILES stringOC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3C(=O)NC=Nc23
Code
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I4125-100G
Unit:100G
List Price: £306.00
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I4125-10G
Unit:10G
List Price: £62.10
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I4125-1G
Unit:1G
List Price: £20.60
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I4125-5G
Unit:5G
List Price: £58.80
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Cas Number58-63-9
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