alpha-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, >=99.0% (HPLC)

Code: 70990-250MG-F D2-231

Application

α-CHCA was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF.

General description

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Application

α-CHCA was used as matrix in improving the detection of low concentration protein digests on MALDI-TOF.

General description

α-Cyano-4-hydroxycinnamic acid (α-CHCA) is widely used as a matrix in order to facilitate ionization of peptides and proteins in a matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometer.

Other Notes

Matrix substance used in MALDI-MS (matrix-assisted laser desorption ionization MS) peptide analysis in proteomics.

absorption≥2000 at 337 nm (mol. absorption)
analyte chemical class(es)glycans, peptides, proteins
assay≥99.0% (HPLC)
cation tracesNa: ≤10 mg/kg, Cr: ≤5 mg/kg, Mn: ≤5 mg/kg, Mg: ≤5 mg/kg, Ca: ≤10 mg/kg, Pb: ≤5 mg/kg, Cu: ≤5 mg/kg, Ba: ≤5 mg/kg, K: ≤5 mg/kg, Zn: ≤5 mg/kg, Ni: ≤5 mg/kg, Cd: ≤5 mg/kg, Co: ≤5 mg/kg
formsolid
gradematrix substance for MALDI-MS
InChI keyAFVLVVWMAFSXCK-VMPITWQZSA-N
InChI1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
mp245-250 °C, 245-250 °C (lit.)
Quality Level100
SMILES stringOC(=O)C(=Cc1ccc(O)cc1)C#N
solubilitymethanol: 10 mg/mL, clear
technique(s)MALDI-MS: suitable
Code
Description
Unit Size
List Price
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70990-1G-F
alpha-Cyano-4-hydroxycinnamic acid, matrix substance for MALDI-MS, >=99.0% (HPLC)

Unit:1G
List Price: £68.40
Source:List Price
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Cas Number28166-41-8
This product has met the following criteria: