Netropsin dihydrochloride, from Streptomyces netropsis, >=98% (HPLC and TLC), powder

Code: N9653-5MG D2-231

Biochem/physiol Actions

Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it pro...


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£167.00 5MG
£200.40 inc. VAT
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Biochem/physiol Actions

Netropsin is an unusual n-methylpyrrole-containing oligopeptide that binds to AT-rich sequences of dsDNA, especially in the minor groove. Thus, it protects such regions from DNase I and other endonucleases, and also inhibits topoisomerases. Netropsin disrupts the cell cycle, prolonging G and arresting in G.

Caution

Protect from light.

Packaging

5 mg in glass bottle

antibiotic activity spectrumGram-positive bacteria, Gram-negative bacteria, viruses
assay≥98% (HPLC and TLC)
biological sourceStreptomyces netropsis
colorfaintly yellow
formpowder
InChI keySDRHUASONSRLFR-UHFFFAOYSA-N
InChI1S/C18H26N10O3.2ClH/c1-27-9-11(6-12(27)16(30)23-4-3-14(19)20)26-17(31)13-5-10(8-28(13)2)25-15(29)7-24-18(21)22;;/h5-6,8-9H,3-4,7H2,1-2H3,(H3,19,20)(H,23,30)(H,25,29)(H,26,31)(H4,21,22,24);2*1H
mode of actionDNA synthesis | interferes
Quality Level200
SMILES string[H]Cl.[H]Cl.NC(CCNC(C1=CC(NC(C2=CC(NC(CNC(N)=N)=O)=CN2C)=O)=CN1C)=O)=N
solubilityH2O: 1 mg/mL
storage temp.−20°C
Cas Number18133-22-7
Hazard Class6.1
Un Number2811
Pack GroupIII
This product has met the following criteria: