Application

Rabbit Anti-Mouse IgG Antibody, HRP conjugate has been used in western blotting. (1:2000)(1:200000) (1:5000)

Biochem/physiol Actions

Immunoglobulin G (IgG) aids in the activation of the complement system. It neutralizes virus particles and toxins. IgG facilitates antibody-dependent cell-mediated cytotoxicity (ADCC). Maternal IgG is transferred to the fetus through the placenta that is crucial for protecting newborns against infectious diseases. Detection of IgG levels in severe acute respiratory syndrome coronavirus (SARS‐CoV)‐2 infected patients can be a potential strategy to assess the severity and prognosis of coronavirus disease 2019 (COVID‐19).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

General description

Immunoglobulin G (IgG) is the most abundant glycoprotein antibody found in human serum. It is secreted by the B cells. IgG structure contains four polypeptide chains, which include two identical heavy (H) chains and two identical λ light (L) chains. These chains are inter-linked by disulfide bonds. IgG exists in four isotypes IgG1, IgG2, IgG3, and IgG4.

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